DSIP
Circadian ResearchCAS 62568-57-4
Available sizes: 5 mg, 10 mg, 15 mg
A peptide named for an effect still under debate
DSIP is the nonapeptide Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu, identified by Schoenenberger and Monnier in the 1970s in blood drawn from rabbits during induced slow-wave sleep. The name encodes the original hypothesis: that this was the humoral factor carrying a sleep signal.
That hypothesis has not been cleanly confirmed. Replication has been inconsistent, and no receptor has been definitively characterised — which for a peptide this old is a genuinely open problem rather than a gap nobody has got to.
What is actually studied
Sleep architecture. Effects on slow-wave and REM proportions in animal models, with results that vary between laboratories.
Circadian and neuroendocrine measures, including reported interactions with corticotropin and somatotropin release.
Stress response models, where it is examined for effects independent of sleep.
Receptor identification — still unresolved, and a research goal in itself.
Blood-brain barrier transport, since a peripherally isolated peptide acting centrally has to get there somehow.
Documentation and verification
Certificates of Analysis are published for tested products and batches. A certificate is a batch-specific record: it reports what was measured, by which method, on a stated date, against a batch identifier. It is evidence about the sample analysed at the time of analysis, and it is silent on attributes it does not list and on what has happened to the material since.
The batch number is the field that connects the document to a physical vial. Where the identifier on a vial does not appear on a certificate, the certificate does not describe that vial, however thorough the analysis behind it was. Batch records can be searched directly, and the guides below explain what each field establishes and what it does not.
- Verify a batchSearch a batch number for the certificate records published against it.
- How to read a certificate of analysisWhat each field reports, and the limits of what a certificate can establish.
- Certificate, specification and safety data sheetThree documents that answer three different questions.
- Storage and handlingWhat defined storage conditions mean, and why cold slows degradation.
- Batch numbers and traceabilityHow an identifier ties material to the analysis describing it.
Supplied for laboratory research use only. Not for human or veterinary use.