Kisspeptin-10
Growth Factor Research
Available sizes: 5 mg, 10 mg
The gatekeeper of the reproductive axis
Kisspeptin-10 is the C-terminal decapeptide of the KISS1 gene product, retaining full activity at KISS1R. The gene was originally identified in cancer metastasis research — the name derives from that work, not from reproduction.
Its role became clear when loss-of-function mutations in GPR54 were found to cause failure of puberty. Kisspeptin neurons act immediately upstream of GnRH neurons, making them the control point of the hypothalamic-pituitary-gonadal axis rather than one input among many.
Research areas
GnRH pulse generation, and how it is gated
Puberty onset and its timing, the finding that established the field
Metabolic gating of reproduction — kisspeptin neurons respond to leptin, linking energy status to fertility
Hypothalamic amenorrhoea and functional reproductive suppression
Fertility research, where kisspeptin has been trialled as an alternative trigger to hCG
Documentation and verification
Certificates of Analysis are published for tested products and batches. A certificate is a batch-specific record: it reports what was measured, by which method, on a stated date, against a batch identifier. It is evidence about the sample analysed at the time of analysis, and it is silent on attributes it does not list and on what has happened to the material since.
The batch number is the field that connects the document to a physical vial. Where the identifier on a vial does not appear on a certificate, the certificate does not describe that vial, however thorough the analysis behind it was. Batch records can be searched directly, and the guides below explain what each field establishes and what it does not.
- Verify a batchSearch a batch number for the certificate records published against it.
- How to read a certificate of analysisWhat each field reports, and the limits of what a certificate can establish.
- Certificate, specification and safety data sheetThree documents that answer three different questions.
- Storage and handlingWhat defined storage conditions mean, and why cold slows degradation.
- Batch numbers and traceabilityHow an identifier ties material to the analysis describing it.
Supplied for laboratory research use only. Not for human or veterinary use.