CJC-1295 + Ipamorelin
Peptide Blends
Available sizes: 10 mg
Two receptors, one axis
This vial contains CJC-1295, an analogue of growth hormone releasing hormone, and Ipamorelin, a selective agonist at the growth hormone secretagogue receptor.
They converge on the same endocrine axis by different routes. CJC-1295 binds the GHRH receptor on somatotroph cells; Ipamorelin binds GHS-R1a, the receptor ghrelin acts at. Because the inputs are independent, the combination is a standard preparation for studying how the axis integrates more than one signal.
What the combination is used to examine
Whether dual-receptor stimulation alters the amplitude or pattern of secretion relative to either compound alone
Pulsatility — GHRH analogues and secretagogues affect the shape of a secretory pulse differently
Selectivity, since Ipamorelin is studied specifically for acting with little effect on cortisol and prolactin compared with earlier secretagogues
Downstream IGF-1 signalling as a measured endpoint
Receptor desensitisation under repeated stimulation
A note on CJC-1295 forms
CJC-1295 appears in the literature both with and without the DAC (Drug Affinity Complex) modification, and the two behave very differently — DAC binds serum albumin and extends the half-life substantially. Which form a study used is a material detail when comparing results, and the certificate of analysis for a batch records the form supplied.
Read alongside
Both constituents individually: CJC-1295 and Ipamorelin. The earlier-generation secretagogues GHRP-2 and GHRP-6 are the usual selectivity comparators, and Sermorelin is the shorter-acting GHRH analogue.
Documentation and verification
Certificates of Analysis are published for tested products and batches. A certificate is a batch-specific record: it reports what was measured, by which method, on a stated date, against a batch identifier. It is evidence about the sample analysed at the time of analysis, and it is silent on attributes it does not list and on what has happened to the material since.
The batch number is the field that connects the document to a physical vial. Where the identifier on a vial does not appear on a certificate, the certificate does not describe that vial, however thorough the analysis behind it was. Batch records can be searched directly, and the guides below explain what each field establishes and what it does not.
- Verify a batchSearch a batch number for the certificate records published against it.
- How to read a certificate of analysisWhat each field reports, and the limits of what a certificate can establish.
- Certificate, specification and safety data sheetThree documents that answer three different questions.
- Storage and handlingWhat defined storage conditions mean, and why cold slows degradation.
- Batch numbers and traceabilityHow an identifier ties material to the analysis describing it.
Supplied for laboratory research use only. Not for human or veterinary use.